open-babel

Install command:
brew install open-babel

Chemical toolbox

https://github.com/openbabel/openbabel

License: GPL-2.0-only

Development: Pull requests

Formula JSON API: /api/formula/open-babel.json

Formula code: open-babel.rb on GitHub

Bottle (binary package) installation support provided for:

macOS on
Apple Silicon
tahoe
sequoia
sonoma
macOS on
Intel
sonoma
Linux ARM64
x86_64

Current versions:

stable 3.2.1
head ⚡️ HEAD

Depends on:

cairo 1.18.4 Vector graphics library with cross-device output support
eigen 5.0.1 C++ template library for linear algebra
inchi 1.07.5 IUPAC International Chemical Identifier
python@3.14 3.14.7 Interpreted, interactive, object-oriented programming language

Depends on when building from source:

cmake 4.4.3 Cross-platform make
pkgconf 3.0.7 Package compiler and linker metadata toolkit
rapidjson 1.1.0 JSON parser/generator for C++ with SAX and DOM style APIs
swig 4.5.1 Generate scripting interfaces to C/C++ code

Uses from macOS: libxml2

Conflicts with: surelog (because both install `roundtrip` binaries)

Binaries: obabel, obconformer, obdistgen, obenergy, obfit, obfitall, obgen, obgrep, obminimize, obmm, obprobe, obprop, obrms, obrotamer, obrotate, obspectrophore, obsym, obtautomer, obthermo, roundtrip

Analytics:

30 days90 days365 days
Installs1165942,699
Installs (--HEAD)1511
Installs on Request1165912,681
Installs on Request (--HEAD)1511
Build Errors1